OPN1MW Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P04001 |
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Gene ID | 101060233;2652;728458 |
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Other Names | Medium-wave-sensitive opsin 1, Green cone photoreceptor pigment, Green-sensitive opsin, GOP, OPN1MW, GCP |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | OPN1MW (HGNC:4206) |
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Synonyms | GCP |
Function | Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | The three color pigments are found in the cone photoreceptor cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.
References
Thirumuruganandham, S.P., et al. J Mol Model 15(8):959-969(2009)Ala-Laurila, P., et al. J. Biol. Chem. 284(24):16492-16500(2009)Holmes, M.V., et al. PLoS ONE 4 (12), E7960 (2009)
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