C14orf179 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96FT9 |
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Other Accession | Q9DA69, Q2TBN9, NP_001096034.1, NP_443105.2 |
Gene ID | 112752 |
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Other Names | Intraflagellar transport protein 43 homolog, IFT43, C14orf179 |
Target/Specificity | The synthetic peptide sequence is selected from aa 160-171 of HUMAN IFT43 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | IFT43 (HGNC:29669) |
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Synonyms | C14orf179 |
Function | As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis (PubMed:28400947, PubMed:28973684). Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base (PubMed:21378380). |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, cilium Note=Associated with microtubules (PubMed:22361696). Localized at the distal tip of the cilium (PubMed:28973684) |
Tissue Location | Expressed in the retina, predominantly in the photoreceptor outer segment. |
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Provided below are standard protocols that you may find useful for product applications.
References
Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :
Heilig, R., et al. Nature 421(6923):601-607(2003)
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