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CNNM4 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q6P4Q7
Other Accession NP_064569.3
Additional Information
Gene ID 26504
Other Names Metal transporter CNNM4, Ancient conserved domain-containing protein 4, Cyclin-M4, CNNM4, ACDP4, KIAA1592
Target/Specificity The synthetic peptide sequence is selected from aa 580-593 of HUMAN CNNM4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNNM4
Synonyms ACDP4, KIAA1592
Function Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed. Highly expressed in heart.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq].

References

Polok, B., et al. Am. J. Hum. Genet. 84(2):259-265(2009)
Parry, D.A., et al. Am. J. Hum. Genet. 84(2):266-273(2009)
Guo, D., et al. Mol Pain 1, 15 (2005) :
Michaelides, M., et al. J. Med. Genet. 41(6):468-473(2004)
Wang, C.Y., et al. Gene 306, 37-44 (2003) :
Downey, L.M., et al. Eur. J. Hum. Genet. 10(12):865-869(2002)
Jalili, I.K., et al. J. Med. Genet. 25(11):738-740(1988)

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$ 277.78
Cat# BP5419c
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