|Other Accession||P62966, P62965, P40220, P62964, NP_004369.1|
|Other Names||Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I, CRABP-I, CRABP1, RBP5|
|Target/Specificity||The synthetic peptide sequence is selected from aa 105-118 of HUMAN CRABP1|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
Tang, X.H., et al. Exp. Cell Res. 314(1):38-51(2008)
Uhrig, M., et al. BMC Med 6, 38 (2008) :
Guidez, F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(47):18694-18699(2007)
Tanaka, K., et al. Oncogene 26(44):6456-6468(2007)
Wu, Q., et al. Mol. Cancer 6, 45 (2007) :
Flagiello, D., et al. Cytogenet. Cell Genet. 76 (1-2), 17-18 (1997) :
Liu, W., et al. Biochem. Biophys. Res. Commun. 229(3):922-929(1996)
Eller, M.S., et al. Exp. Cell Res. 198(2):328-336(1992)
Astrom, A., et al. J. Biol. Chem. 266(26):17662-17666(1991)
Ong, D.E. Arch Dermatol 123 (12), 1693-1695A (1987) :
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