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RAB11FIP2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q7L804 |
|---|---|
| Other Accession | NP_055719.1 |
| Clone Names | 91023034 |
| Gene ID | 22841 |
|---|---|
| Other Names | Rab11 family-interacting protein 2, Rab11-FIP2, NRip11, RAB11FIP2, KIAA0941 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RAB11FIP2 |
|---|---|
| Synonyms | KIAA0941 |
| Function | A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics. |
| Cellular Location | Cell projection, phagocytic cup. Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein Note=Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane |
Research Areas
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$ 277.78
Cat# BP5475c
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