RIPK4 (ANKRD3) Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P57078 |
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Clone Names | 2123011 |
Other Names | Receptor-interacting serine/threonine-protein kinase 4, Ankyrin repeat domain-containing protein 3, PKC-delta-interacting protein kinase, RIPK4, ANKRD3, DIK |
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Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7808b was selected from the C-term region of human ANKRD3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RIPK4 |
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Synonyms | ANKRD3, DIK |
Function | Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation. |
Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
Tissue Location | Expressed in hair follicles and skin. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
References
Hattori, M., et al., Nature 405(6784):311-319 (2000).
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