UTS2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95399 |
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Clone Names | 71213153 |
Gene ID | 10911 |
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Other Names | Urotensin-2, Urotensin II, U-II, UII, UTS2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7987a was selected from the N-term region of human UTS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | UTS2 |
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Function | Highly potent vasoconstrictor. |
Cellular Location | Secreted. |
Tissue Location | Brain specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
UTS2 is a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this protein is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
References
Brailoiu,E., Peptides 29 (5), 721-726 (2008)Cirillo,P., J. Thromb. Haemost. 6 (5), 726-736 (2008)Zoccali,C.Hypertension 51 (2), 326-333 (2008)
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