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Human recombinant protein Cyclophilin H
Human Recombinant Cyclophilin H
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O43447 |
|---|---|
| Concentration | 1 |
| Calculated MW | 19.2 kDa |
| Gene ID | 10465 |
|---|---|
| Gene Symbol | PPIH |
| Other Names | Peptidylprolyl isomerase H, CYPH, CYP20, SnuCyp-20, PPIase H, Rotamase H |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MAVANSSPVN PVVFFDVSIG GQEVGRMKIE LFADVVPKTA ENFRQFCTGE FRKDGVPIGY KGSTFHRVIK DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN GCQFFITCSK CDWLDGKHVV FGKIIDGLLV MRKIENVPTG PNNKPKLPVV ISQCGEM |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in PBS (pH 7.4) containing 10% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cyclophilin H is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. The cyclophilin H is a specific component of the human U4/U6 small nuclear ribonucleoprotein particle involved in the nuclear splicing of pre-mRNA. It stably associates with the U4/U6-60kD and -90kD proteins, the human orthologues of the Saccharomyces cerevisiae Prp4 and Prp3 splicing factors.
References
Horowitz D.S.,et al.RNA 3:1374-1387(1997).
Teigelkamp S.,et al.RNA 4:127-141(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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