|Calculated MW||14.2 kDa|
|Other Names||Peptidyl-prolyl cis-trans isomerase FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase|
|Sequence||MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE|
|Storage||-80°C; 0.25 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 20% glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) belongs to the immunophilin protein family which has a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP1B is a cis-trans prolyl isomerase which binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). FKBP1B is extremely similar to the FK506-binding protein 1A. The physiological role of FKBP1B is thought to be in excitation-contraction coupling in cardiac muscle.
Arakawa H.,et al.Biochem. Biophys. Res. Commun. 200:836-843(1994).
Lam E.,et al.J. Biol. Chem. 270:26511-26522(1995).
Seidler T.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Nakazawa T.,et al.Gene 360:55-64(2005).
Hillier L.W.,et al.Nature 434:724-731(2005).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.