ACY3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| FC, WB, E |
|---|---|
| Primary Accession | Q96HD9 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35241 Da |
| Antigen Region | 66-95 aa |
| Gene ID | 91703 |
|---|---|
| Other Names | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, ACY-3, Aspartoacylase-2, Hepatitis C virus core-binding protein 1, HCBP1, HCV core-binding protein 1, ACY3, ASPA2 |
| Target/Specificity | This ACY3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the Central region of human ACY3. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ACY3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACY3 |
|---|---|
| Synonyms | ASPA2 |
| Function | Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). |
| Cellular Location | Apical cell membrane; Peripheral membrane protein. Cytoplasm Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm |

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Provided below are standard protocols that you may find useful for product applications.
Background
ACY3 belongs to the aspA/astE family. Aspartoacylase subfamily. Catalytic activity: N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate
References
Chen,Y.R., et.al., J. Gastroenterol. Hepatol. 24 (7), 1300-1304 (2009)
Pushkin,A., et.al., Am. J. Physiol., Cell Physiol. 286 (4), C848-C856 (2004)
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