Anti-TCF3 TCF7L1 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
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Primary Accession | Q9HCS4 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-TCF3 TCF7L1 Rabbit Monoclonal Antibody . Tested in WB, Flow Cytometry applications. This antibody reacts with Human. |
Gene ID | 83439 |
---|---|
Other Names | Transcription factor 7-like 1, HMG box transcription factor 3, TCF-3, TCF7L1, TCF3 |
Calculated MW | 62631 MW KDa |
Application Details | WB 1:500-1:2000 FC 1:50 |
Subcellular Localization | Nucleus. |
Tissue Specificity | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium.. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: CAH-20 |
Immunogen | A synthesized peptide derived from human TCF3 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | TCF7L1 |
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Synonyms | TCF3 |
Function | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. |
Cellular Location | Nucleus. |
Tissue Location | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium |

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