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> home > Products > Primary Antibodies > Signal Transduction > Anti-MKLP1 KIF23 Rabbit Monoclonal Antibody
Anti-MKLP1 KIF23 Rabbit Monoclonal Antibody
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Application 
| WB, IF, ICC |
|---|---|
| Primary Accession | Q02241 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-MKLP1 KIF23 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 9493 |
|---|---|
| Other Names | Kinesin-like protein KIF23, Kinesin-like protein 5, Mitotic kinesin-like protein 1, KIF23, KNSL5, MKLP1 |
| Calculated MW | 110059 MW KDa |
| Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 |
| Subcellular Localization | Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: EG-11 |
| Immunogen | A synthesized peptide derived from human MKLP1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | KIF23 |
|---|---|
| Synonyms | KNSL5, MKLP1 |
| Function | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| Cellular Location | Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis |
| Tissue Location | Widely expressed.. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13570
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