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> home > Products > Primary Antibodies > Signal Transduction > Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody
Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q99731 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human. |
| Gene ID | 6363 |
|---|---|
| Other Names | C-C motif chemokine 19, Beta-chemokine exodus-3, CK beta-11, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, ELC, Macrophage inflammatory protein 3 beta, MIP-3-beta, Small-inducible cytokine A19, CCL19, ELC, MIP3B, SCYA19 |
| Calculated MW | 10993 MW KDa |
| Application Details | WB 1:500-1:2000 |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AHD-3 |
| Immunogen | A synthesized peptide derived from human CCL19 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | CCL19 |
|---|---|
| Synonyms | ELC, MIP3B, SCYA19 |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta- arrestin (ARRB1/2) to ACKR4. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach |
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Application Protocols
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$ 370.00
Cat# ABO13592
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