Anti-CCL19 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | Q99731 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 10993 Da |
Gene ID | 6363 |
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Other Names | ELC; MIP3B; SCYA19; C-C motif chemokine 19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19 |
Target/Specificity | Recognizes endogenous levels of CCL19 protein. |
Dilution | WB~~1/500 - 1/1000 IH~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | CCL19 |
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Synonyms | ELC, MIP3B, SCYA19 |
Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta- arrestin (ARRB1/2) to ACKR4. |
Cellular Location | Secreted. |
Tissue Location | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to CCL19
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