Anti-Plectin Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, IP |
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Primary Accession | Q15149 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Plectin Rabbit Monoclonal Antibody . Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 5339 |
---|---|
Other Names | Plectin, PCN, PLTN, Hemidesmosomal protein 1, HD1, Plectin-1, PLEC, PLEC1 |
Calculated MW | 531791 MW KDa |
Application Details | WB 1:1000-1:2000 IHC 1:50-1:100 IP 1:30 |
Subcellular Localization | Cytoplasm, cytoskeleton. Cell junction, hemidesmosome. |
Tissue Specificity | Widely expressed with highest levels in muscle, heart, placenta and spinal cord. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: AFE-16 |
Immunogen | A synthesized peptide derived from human Plectin |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | PLEC |
---|---|
Synonyms | PLEC1 |
Function | Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity. |
Cellular Location | Cytoplasm, cytoskeleton. Cell junction, hemidesmosome. Cell projection, podosome {ECO:0000250|UniProtKB:Q9QXS1}. Note=Localized to the cortex of myotube podosomes. {ECO:0000250|UniProtKB:Q9QXS1} |
Tissue Location | Widely expressed with highest levels in muscle, heart, placenta and spinal cord |

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