Anti-Aggrecan Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC |
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Primary Accession | P16112 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Aggrecan Rabbit Monoclonal Antibody . Tested in IHC application. This antibody reacts with Human. |
Gene ID | 176 |
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Other Names | Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, Aggrecan core protein 2, ACAN, AGC1, CSPG1, MSK16 |
Calculated MW | 261329 Da |
Application Details | IHC 1:50-1:200 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 17A33 |
Immunogen | A synthesized peptide derived from human Aggrecan |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | ACAN |
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Synonyms | AGC1, CSPG1, MSK16 |
Function | This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P07898} |
Tissue Location | Detected in fibroblasts (at protein level) (PubMed:36213313). Restricted to cartilage (PubMed:7524681) |

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