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Anti-NKX3.1 Rabbit Monoclonal Antibody

     
  •  - Anti-NKX3.1 Rabbit Monoclonal Antibody ABO15345
    Western blot analysis of Nkx3.1 expression in LNCaP cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q99801
Host Rabbit
Isotype IgG
Reactivity Human
Clonality Monoclonal
Format Liquid
Description Anti-NKX3.1 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human.
Additional Information
Gene ID 4824
Other Names Homeobox protein Nkx-3.1, Homeobox protein NK-3 homolog A, NKX3-1 (HGNC:7838)
Calculated MW 26350 Da
Application Details WB 1:500-1:1000
IHC 1:50-1:200
Contents Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names Clone: 19N21
Immunogen A synthesized peptide derived from human Nkx3.1
Purification Affinity-chromatography
Storage Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Information
Name NKX3-1 (HGNC:7838)
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:11137288}
Tissue Location Highly expressed in the prostate and, at a lower level, in the testis.
Citations (0)
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$ 370.00
Cat# ABO15345
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