Anti-NKX3.1 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
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Primary Accession | Q99801 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-NKX3.1 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
Gene ID | 4824 |
---|---|
Other Names | Homeobox protein Nkx-3.1, Homeobox protein NK-3 homolog A, NKX3-1 (HGNC:7838) |
Calculated MW | 26350 Da |
Application Details | WB 1:500-1:1000 IHC 1:50-1:200 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 19N21 |
Immunogen | A synthesized peptide derived from human Nkx3.1 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | NKX3-1 (HGNC:7838) |
---|---|
Function | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:11137288} |
Tissue Location | Highly expressed in the prostate and, at a lower level, in the testis. |

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