Anti-ORP1 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IF, ICC, FC |
---|---|
Primary Accession | Q9BXW6 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-ORP1 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 114876 |
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Other Names | Oxysterol-binding protein-related protein 1, ORP-1, OSBP-related protein 1, OSBPL1A (HGNC:16398) |
Calculated MW | 50,108 kDa |
Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 FC 1:50 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 27O45 |
Immunogen | A synthesized peptide derived from human ORP1 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | OSBPL1A (HGNC:16398) |
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Function | Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193). |
Cellular Location | Late endosome. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes |

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