Anti-delta 2 Catenin Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | Q9UQB3 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-delta 2 Catenin Rabbit Monoclonal Antibody . Tested in WB, ICC/IF applications. This antibody reacts with Mouse, Rat. |
| Gene ID | 1501 |
|---|---|
| Other Names | Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, CTNND2, NPRAP |
| Calculated MW | 132656 Da |
| Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 31C89 |
| Immunogen | A synthesized peptide derived from human delta 2 Catenin |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | CTNND2 |
|---|---|
| Synonyms | NPRAP |
| Function | Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:25807484). Involved in the regulation of Wnt signaling (PubMed:25807484). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:O35927}. Cell junction, adherens junction {ECO:0000250|UniProtKB:O35927}. Cell projection, dendrite {ECO:0000250|UniProtKB:O35116}. Perikaryon |
| Tissue Location | Expressed in brain; highest expression is observed in fetal brain (PubMed:25807484). |

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