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Anti-delta 2 Catenin Rabbit Monoclonal Antibody

     
  •  - Anti-delta 2 Catenin Rabbit Monoclonal Antibody ABO16718
    Western blot analysis of delta 2 Catenin expression in Mouse brain cell lysate.
    detail
  •  - Anti-delta 2 Catenin Rabbit Monoclonal Antibody ABO16718
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9UQB3
Host Rabbit
Isotype Rabbit IgG
Reactivity Rat, Mouse
Clonality Monoclonal
Format Liquid
Description Anti-delta 2 Catenin Rabbit Monoclonal Antibody . Tested in WB, ICC/IF applications. This antibody reacts with Mouse, Rat.
Additional Information
Gene ID 1501
Other Names Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, CTNND2, NPRAP
Calculated MW 132656 Da
Application Details WB 1:500-1:2000
ICC/IF 1:50-1:200
Contents Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names Clone: 31C89
Immunogen A synthesized peptide derived from human delta 2 Catenin
Purification Affinity-chromatography
Storage Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Information
Name CTNND2
Synonyms NPRAP
Function Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:25807484). Involved in the regulation of Wnt signaling (PubMed:25807484). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.
Cellular Location Nucleus {ECO:0000250|UniProtKB:O35927}. Cell junction, adherens junction {ECO:0000250|UniProtKB:O35927}. Cell projection, dendrite {ECO:0000250|UniProtKB:O35116}. Perikaryon
Tissue Location Expressed in brain; highest expression is observed in fetal brain (PubMed:25807484).
Research Areas
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$ 370.00
Cat# ABO16718
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