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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-ICOS ligand / B7-H2 Antibody
Goat anti-ICOS ligand / B7-H2 Antibody
Peptide-affinity purified goat antibody
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- BACKGROUND
Application 
| WB, Pep-ELISA |
|---|---|
| Primary Accession | O75144 |
| Other Accession | NP_056074.1, NP_001269979.1, NP_001269980.1, NP_001269981.1 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | ICOSLG |
| Calculated MW | 33349 Da |
| Gene ID | 23308 |
|---|---|
| Other Names | ICOSLG; inducible T-cell co-stimulator ligand; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS; B7 homolog 2; B7 homologue 2; B7-like protein Gl50; B7-related protein 1; ICOS ligand; transmembrane protein B7-H2 ICOS ligand |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize all reported isoforms (NP_056074.1; NP_001269979.1; NP_001269980.1; NP_001269981.1). |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-ICOS ligand / B7-H2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ICOSLG |
|---|---|
| Synonyms | B7H2, B7RP1, ICOSL, KIAA0653 |
| Function | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells. |
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Application Protocols
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$ 341.00
Cat# AF4344a
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