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> home > Products > Primary Antibodies > Antibody Collections > Head neck negative > KD-Validated Anti-B cell receptor associated protein 31 Rabbit Monoclonal Antibody
KD-Validated Anti-B cell receptor associated protein 31 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P51572 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB3680 |
| Calculated MW | Predicted, 28 kDa , observed, 25 kDa |
| Gene Name | BCAP31 |
| Aliases | BCAP31; B Cell Receptor Associated Protein 31; DXS1357E; BAP31; CDM; B-Cell Receptor-Associated Protein 31; 6C6-AG Tumor-Associated Antigen; 6C6-AG; BCR-Associated Protein Bap31; BCR-Associated Protein 31; MICRODELXq28; Protein CDM; P28 Bap31; DELXQ28; 6C6-Ag; Bap31; DDCH; P28 |
| Immunogen | A synthetic peptide of human BCAP31 |
| Gene ID | 10134 |
|---|---|
| Other Names | B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28, BCAP31 (HGNC:16695) |
| Name | BCAP31 (HGNC:16695) |
|---|---|
| Function | Functions as a chaperone protein (PubMed:18287538, PubMed:9396746). Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:18287538, PubMed:9396746). Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:18287538, PubMed:9396746). Also serves as a cargo receptor for the export of transmembrane proteins (By similarity). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022). In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022). May be involved in CASP8-mediated apoptosis (PubMed:10958671). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex (PubMed:9396746). Associates with the mitochondria-associated endoplasmic reticulum membrane via interaction with TOMM40 (PubMed:31206022) |
| Tissue Location | Ubiquitous. Highly expressed in neurons and discrete endocrine cells. |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1221
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