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KD-Validated Anti-Amyloid beta precursor like protein 2 Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-Amyloid beta precursor like protein 2 Rabbit Monoclonal Antibody AGI1367
    Western blotting analysis using anti-Amyloid beta precursor like protein 2 antibody (Cat#61646). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-Amyloid beta precursor like protein 2 antibody (Cat#61646, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
  • WB - KD-Validated Anti-Amyloid beta precursor like protein 2 Rabbit Monoclonal Antibody AGI1367
    Western blotting analysis using anti-Amyloid beta precursor like protein 2 antibody (Cat#61646). Amyloid beta precursor like protein 2 expression in wild type (WT) and amyloid beta precursor like protein 2 shRNA knockdown (KD) Hela cells with 30 µg of total cell lysates. β-Tubulin serves as a loading control. The blot was incubated with anti-Amyloid beta precursor like protein 2 antibody (Cat#61646, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
  • FC - KD-Validated Anti-Amyloid beta precursor like protein 2 Rabbit Monoclonal Antibody AGI1367
    Flow cytometric analysis of Amyloid beta precursor like protein 2 expression in HepG2 cells using Amyloid beta precursor like protein 2 antibody (Cat#61646, 1:2,000). Green, isotype control; red, Amyloid beta precursor like protein 2.
    detail
  • ICC - KD-Validated Anti-Amyloid beta precursor like protein 2 Rabbit Monoclonal Antibody AGI1367
    Immunocytochemical staining of HepG2 cells with Amyloid beta precursor like protein 2 antibody (Cat#61646, 1:1,000). Nuclei were stained blue with DAPI; Amyloid beta precursor like protein 2 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar: 20 µm.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC, ICC
Primary Accession Q06481
Reactivity Human
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 23GB1595
Calculated MW Predicted, 87 kDa , observed, 87-140 kDa
Gene Name APLP2
Aliases APLP2; Amyloid Beta Precursor Like Protein 2; APPH 2; Amyloid Beta (A4) Precursor-Like Protein 2; APPL2; Sperm Membrane Protein YWK-II; CDEI Box-Binding Protein; APLP-2; CDEBP; Amyloid Precursor Protein Homolog HSD-2; Testicular Tissue Protein Li 23; Amyloid Protein Homolog; Amyloid-Like Protein 2
Immunogen A synthesized peptide derived from human APLP2
Additional Information
Gene ID 334
Other Names Amyloid beta precursor like protein 2 {ECO:0000312|HGNC:HGNC:598}, APPH, Amyloid beta (A4) precursor-like protein 2, APLP2 (HGNC:598)
Protein Information
Name APLP2 (HGNC:598)
Function May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Nucleus
Tissue Location Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI1367
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