KD-Validated Anti-Methylthioadenosine phosphorylase Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
---|---|
Primary Accession | Q13126 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 23GB4560 |
Calculated MW | Predicted, 31 kDa , observed, 29 kDa |
Gene Name | MTAP |
Aliases | MTAP; Methylthioadenosine Phosphorylase; MSAP; S-Methyl-5'-Thioadenosine Phosphorylase; 5'-Methylthioadenosine Phosphorylase; MTA Phosphorylase; MTAPase; C86fus; Epididymis Secretory Sperm Binding Protein; Epididymis Luminal Protein 249; MeSAdo Phosphorylase; EC 2.4.2.28; HEL-249; DMSMFH; C86FUS; DMSFH; LGMBF; BDMF |
Immunogen | A synthesized peptide derived from human MTAP |
Gene ID | 4507 |
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Other Names | S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}, 2.4.2.28 {ECO:0000255|HAMAP-Rule:MF_03155}, 5'-methylthioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}, MTA phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}, MTAP {ECO:0000255|HAMAP-Rule:MF_03155}, MTAPase {ECO:0000255|HAMAP-Rule:MF_03155}, MTAP {ECO:0000255|HAMAP-Rule:MF_03155}, MSAP |
Name | MTAP {ECO:0000255|HAMAP-Rule:MF_03155} |
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Synonyms | MSAP |
Function | Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
Cellular Location | Cytoplasm. Nucleus {ECO:0000255|HAMAP- Rule:MF_03155} |
Tissue Location | Ubiquitously expressed. |

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