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KD-Validated Anti-Contactin associated protein 1 Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-Contactin associated protein 1 Rabbit Monoclonal Antibody AGI1531
    Western blotting analysis using anti-Contactin associated protein 1 antibody (Cat#AGI1531). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-Contactin associated protein 1 antibody (Cat#AGI1531, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    detail
  • WB - KD-Validated Anti-Contactin associated protein 1 Rabbit Monoclonal Antibody AGI1531
    Western blotting analysis using anti-Contactin associated protein 1 antibody (Cat#AGI1531). Contactin associated protein 1 expression in wild type (WT) and Contactin associated protein 1 shRNA knockdown (KD) HT-1080 cells with 30 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-Contactin associated protein 1 antibody (Cat#AGI1531, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    detail
  • FC - KD-Validated Anti-Contactin associated protein 1 Rabbit Monoclonal Antibody AGI1531
    Flow cytometric analysis of Contactin associated protein 1 expression in HepG2 cells using Contactin associated protein 1 antibody (Cat#AGI1531, 1:2,000). Green, isotype control; red, Contactin associated protein 1.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC
Primary Accession P78357
Reactivity Human, Mouse
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 23GB5605
Calculated MW Predicted, 156 kDa , observed, 165 kDa
Gene Name CNTNAP1
Aliases CNTNAP1; Contactin Associated Protein 1; P190; CNTNAP; CASPR; NRXN4; Contactin-Associated Protein 1; Neurexin IV; Neurexin-4; Caspr1; Caspr; Neurexin 4; CHN3
Immunogen A synthesized peptide derived from human Caspr
Additional Information
Gene ID 8506
Other Names Contactin-associated protein 1, Caspr, Caspr1, Neurexin IV, Neurexin-4, p190, CNTNAP1, CASPR, NRXN4
Protein Information
Name CNTNAP1
Synonyms CASPR, NRXN4
Function Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Cellular Location Membrane; Single-pass type I membrane protein. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:O54991}
Tissue Location Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI1531
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