KD-Validated Anti-GATAD2A Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
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Primary Accession | Q86YP4 |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 23GB5685 |
Calculated MW | Predicted, 68 kDa , observed , 68 kDa |
Gene Name | GATAD2A |
Aliases | GATAD2A; GATA Zinc Finger Domain Containing 2A; GATA Zinc Finger Domain-Containing Protein 2A; Transcriptional Repressor P66-Alpha; P66alpha; P66 Alpha; Hp66alpha; P66ALPHA |
Immunogen | A synthesized peptide derived from human p66 alpha |
Gene ID | 54815 |
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Other Names | Transcriptional repressor p66-alpha, Hp66alpha, GATA zinc finger domain-containing protein 2A, GATAD2A |
Name | GATAD2A |
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Function | Transcriptional repressor (PubMed:12183469, PubMed:16415179). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666). Enhances MBD2-mediated repression (PubMed:12183469, PubMed:16415179). Efficient repression requires the presence of GATAD2B (PubMed:16415179). |
Cellular Location | Nucleus speckle. Nucleus. Chromosome. Note=Speckled nuclear localization requires both CR1 and CR2 regions (PubMed:16415179). Localizes to sites of DNA damage in a manner partially dependent on ZMYND8 (PubMed:27732854). |
Tissue Location | Ubiquitous, both in fetal and adult tissues. |

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