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KD-Validated Anti-FANCC Mouse Monoclonal Antibody

Mouse monoclonal antibody

     
  • WB - KD-Validated Anti-FANCC Mouse Monoclonal Antibody AGI2046
    Western blotting analysis using anti-FANCC antibody (Cat#63882). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-FANCC antibody (Cat#63882, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
  • WB - KD-Validated Anti-FANCC Mouse Monoclonal Antibody AGI2046
    Western blotting analysis using anti-FANCC antibody (Cat#63882). FANCC expression in wild type (WT) and FANCC shRNA knockdown (KD) HeLa cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-FANCC antibody (Cat#63882, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q00597
Reactivity Human
Clonality Monoclonal
Isotype Mouse IgG1
Clone Names 24GB8340
Calculated MW Predicted, 63 kDa, observed, 55 kDa
Gene Name FANCC
Aliases FANCC; FA Complementation Group C; FAC; FACC; FA3; Fanconi Anemia Complementation Group C; Fanconi Anemia Group C Protein; Protein FACC
Immunogen Recombinant protein of human FANCC
Additional Information
Gene ID 2176
Other Names Fanconi anemia group C protein, Protein FACC, FANCC, FAC, FACC
Protein Information
Name FANCC
Synonyms FAC, FACC
Function DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
Cellular Location Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic
Tissue Location Ubiquitous.
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2046
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