KD-Validated Anti-ASRGL1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
---|---|
Primary Accession | Q7L266 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2a |
Clone Names | 24GB14265 |
Calculated MW | Predicted, 32 kDa, observed, 40 kDa |
Gene Name | ASRGL1 |
Aliases | ASRGL1; Asparaginase And Isoaspartyl Peptidase 1; ALP; ALP1; Isoaspartyl Peptidase/L-Asparaginase; Asparaginase-Like 1 Protein; L-Asparagine Amidohydrolase; Asparaginase-Like Protein 1; Beta-Aspartyl-Peptidase; Isoaspartyl Dipeptidase; Asparaginase Like 1; EC 3.5.1.1; FLJ22316; CRASH; Testis Secretory Sperm-Binding Protein Li 242mP; L-Asparaginase; EC 3.4.19.5 |
Immunogen | Recombinant protein of human ASRGL1 |
Gene ID | 80150 |
---|---|
Other Names | Isoaspartyl peptidase/L-asparaginase, 3.4.19.5, 3.5.1.1, Asparaginase-like protein 1, Beta-aspartyl-peptidase, Isoaspartyl dipeptidase, L-asparagine amidohydrolase, Isoaspartyl peptidase/L-asparaginase alpha chain, Isoaspartyl peptidase/L-asparaginase beta chain, ASRGL1, ALP, CRASH |
Name | ASRGL1 |
---|---|
Synonyms | ALP, CRASH |
Function | Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp- L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. |
Cellular Location | Cytoplasm. Note=Midpiece of sperm tail |
Tissue Location | Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over- expressed in uterine, mammary, prostatic and ovarian carcinoma |

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