KD-Validated Anti-POLDIP2 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | Q9Y2S7 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4415 |
| Calculated MW | Predicted, 42 kDa; observed, 35 kDa |
| Gene Name | POLDIP2 |
| Aliases | POLDIP2; DNA Polymerase Delta Interacting Protein 2; PDIP38; Polymerase (DNA-Directed), Delta Interacting Protein 2; 38 KDa DNA Polymerase Delta Interaction Protein; Polymerase Delta-Interacting Protein 2; DKFZP586F1524; POLD4; P38; Polymerase (DNA) Delta Interacting Protein 2; Polymerase Delta Interacting Protein 38 |
| Immunogen | A synthesized peptide derived from human POLDIP2 |
| Gene ID | 26073 |
|---|---|
| Other Names | Polymerase delta-interacting protein 2, 38 kDa DNA polymerase delta interaction protein, p38, POLDIP2 {ECO:0000303|PubMed:26984527, ECO:0000312|HGNC:HGNC:23781} |
| Name | POLDIP2 {ECO:0000303|PubMed:26984527, ECO:0000312|HGNC:HGNC:23781} |
|---|---|
| Function | Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) (PubMed:24191025, PubMed:26984527). |
| Cellular Location | Mitochondrion matrix. Nucleus Note=Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus. |

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