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CLIC2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O15247 |
| Other Accession | NM_001289, NP_001280 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog |
| Predicted | Human, Rat, Rabbit, Pig, Chicken, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27kDa |
| Gene ID | 1193 |
|---|---|
| Alias Symbol | CLIC2b, XAP121 |
| Other Names | Chloride intracellular channel protein 2, XAP121, CLIC2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-CLIC2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CLIC2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CLIC2 |
|---|---|
| Function | Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. |
| Cellular Location | Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain |
| Tissue Location | Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis Expressed in fetal thymus and kidney. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Fan,L., et al., (2003) FEBS Lett. 540 (1-3), 77-80Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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