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KBTBD10 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O60662 |
| Other Accession | NM_006063, NP_006054 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog |
| Predicted | Mouse, Rabbit, Pig, Chicken, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 68kDa |
| Gene ID | 10324 |
|---|---|
| Alias Symbol | SARCOSIN, KBTBD10 |
| Other Names | Kelch-like protein 41, Kel-like protein 23, Kelch repeat and BTB domain-containing protein 10, Kelch-related protein 1, Sarcosin, KLHL41, KBTBD10, KRP1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-KBTBD10 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | KBTBD10 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KLHL41 |
|---|---|
| Synonyms | KBTBD10, KRP1 |
| Function | Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells. |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A2AUC9}. Cell projection, pseudopodium {ECO:0000250|UniProtKB:Q9ER30}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q9ER30}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:A2AUC9} Sarcoplasmic reticulum membrane Endoplasmic reticulum membrane Note=Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia. |
| Tissue Location | Sarcomeric muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Lim,D.S., et al., (2001) J. Am. Coll. Cardiol. 38 (4), 1175-1180Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:du Puy, L. et al. Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments. Int. J. Dev. Biol. 56, 301-9 (2012). WB, Mouse, Bovine, H, Rabbit, Rat, Guinea pig, Human, Dog22562206
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