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SLC38A8 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - SLC38A8 Antibody - C-terminal region AI15970

    Host: Rabbit
    Target Name: SLC38A8
    Sample Tissue: Fetal Brain lysates
    Antibody Dilution: 1.0μg/ml
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession A6NNN8
Other Accession NM_001080442, NP_001073911
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Additional Information
Gene ID 146167
Other Names Putative sodium-coupled neutral amino acid transporter 8, Solute carrier family 38 member 8, SLC38A8
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-SLC38A8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSLC38A8 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC38A8 {ECO:0000250|UniProtKB:Q5HZH7, ECO:0000312|HGNC:HGNC:32434}
Function Electrogenic sodium-dependent amino acid transporter with a preference for L-glutamine, L-alanine, L-histidine, L-aspartate and L- arginine. May facilitate glutamine uptake in both excitatory and inhibitory neurons. The transport mechanism and stoichiometry remain to be elucidated.
Cellular Location Membrane {ECO:0000250|UniProtKB:Q5HZH7}; Multi- pass membrane protein. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q5HZH7}. Cell projection, axon {ECO:0000250|UniProtKB:Q5HZH7}
Tissue Location Expressed in fetal and adult brain, and spinal cord. In the brain, it is localized in the cell body and axon of the majority of neuronal cells and in a subset of glial cells. Found throughout the neuronal retina, with higher expression levels in the inner and outer plexiform layers and the photoreceptor layer. Very weak expression is also present in the kidneys, thymus, and testes
Research Areas
Citations (0)
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Background

Putative sodium-dependent amino acid/proton antiporter.

References

Martin J.,et al.Nature 432:988-994(2004).
Poulter J.A.,et al.Am. J. Hum. Genet. 93:1143-1150(2013).
Perez Y.,et al.Eur. J. Hum. Genet. 22:703-706(2014).

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$ 389.00
Cat# AI15970
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