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SLC38A8 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A6NNN8 |
| Other Accession | NP_001073911.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46731 Da |
| Antigen Region | 149-177 aa |
| Gene ID | 146167 |
|---|---|
| Other Names | Putative sodium-coupled neutral amino acid transporter 8, Solute carrier family 38 member 8, SLC38A8 |
| Target/Specificity | This SLC38A8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the Central region of human SLC38A8. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLC38A8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC38A8 {ECO:0000250|UniProtKB:Q5HZH7, ECO:0000312|HGNC:HGNC:32434} |
|---|---|
| Function | Electrogenic sodium-dependent amino acid transporter with a preference for L-glutamine, L-alanine, L-histidine, L-aspartate and L- arginine. May facilitate glutamine uptake in both excitatory and inhibitory neurons. The transport mechanism and stoichiometry remain to be elucidated. |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:Q5HZH7}; Multi- pass membrane protein. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q5HZH7}. Cell projection, axon {ECO:0000250|UniProtKB:Q5HZH7} |
| Tissue Location | Expressed in fetal and adult brain, and spinal cord. In the brain, it is localized in the cell body and axon of the majority of neuronal cells and in a subset of glial cells. Found throughout the neuronal retina, with higher expression levels in the inner and outer plexiform layers and the photoreceptor layer. Very weak expression is also present in the kidneys, thymus, and testes |
Research Areas
Citations (0)
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Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
SLC38A8 is a putative sodium-dependent amino acid/proton antiporter (By similarity).
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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$ 385.00
$ 150.00
Cat# AP12688c
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