EDNRB / Endothelin B Receptor Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, ICC |
---|---|
Primary Accession | P24530 |
Reactivity | Human, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50kDa |
Dilution | IHC-P (4-11 µg/ml) |
Gene ID | 1910 |
---|---|
Other Names | Endothelin B receptor, ET-B, ET-BR, Endothelin receptor non-selective type, EDNRB, ETRB |
Target/Specificity | Human EDNRB. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTPN5 (68%). |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | EDNRB / Endothelin B Receptor Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EDNRB (HGNC:3180) |
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Synonyms | ETRB |
Function | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins. |
Tissue Location | Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells |
Volume | 50 µl |

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Provided below are standard protocols that you may find useful for product applications.
Background
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
References
Nakamuta M.,et al.Biochem. Biophys. Res. Commun. 177:34-39(1991).
Ogawa Y.,et al.Biochem. Biophys. Res. Commun. 178:248-255(1991).
Sakamoto A.,et al.Biochem. Biophys. Res. Commun. 178:656-663(1991).
Haendler B.,et al.J. Cardiovasc. Pharmacol. 20:S1-S4(1992).
Arai H.,et al.Jpn. Circ. J. 56:1303-1307(1992).

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