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IRX3 Antibody (aa271-320)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | P78415 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 52kDa |
| Dilution | ELISA (1:20000), IHC-P (5 µg/ml), |
| Gene ID | 79191 |
|---|---|
| Other Names | Iroquois-class homeodomain protein IRX-3, Homeodomain protein IRXB1, Iroquois homeobox protein 3, IRX3, IRXB1 |
| Target/Specificity | IRX3 Antibody detects endogenous levels of total IRX3 protein. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | IRX3 Antibody (aa271-320) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IRX3 |
|---|---|
| Synonyms | IRXB1 |
| Function | Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism. |
| Cellular Location | Nucleus. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).
References
Hansen L.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Lewis M.T.,et al.Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
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