Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
CD27 Antibody (clone M-T271)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E, FC |
|---|---|
| Primary Accession | P26842 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | M-T271 |
| Calculated MW | 29kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 939 |
|---|---|
| Other Names | CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7 |
| Target/Specificity | Dimeric CD27 molecule of approximately 110 kd but does not block the interaction between CD70 and CD27. Clone M-T271 has been shown to abrogate IL-4 production or induce apoptosis in MLR. |
| Reconstitution & Storage | Store at +4°C. DO NOT FREEZE. |
| Precautions | CD27 Antibody (clone M-T271) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CD27 |
|---|---|
| Synonyms | TNFRSF7 |
| Function | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Found in most T-lymphocytes. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
References
Camerini D.,et al.J. Immunol. 147:3165-3169(1991).
Loenen W.A.,et al.J. Immunol. 149:3937-3943(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
