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Anti-Adenylate Cyclase III Antibody

Our Anti-Adenylate Cyclase III primary antibody from PhosphoSolutions is rabbit polyclonal. It detec

     
  •  - Anti-Adenylate Cyclase III Antibody AN1298
    Immunofluorescence of a section of rat hippocampus selectively labeling the neuronal cilia with anti-adenylate cyclase III (cat. 85-AC3, 1:10,000, red), labeling nuclei with anti-MECP2 (cat. 1205-MeCP2, 1:1000,green), and Hoechst staining of nuclear DNA.
    detail
  •  - Anti-Adenylate Cyclase III Antibody AN1298
    Immunostaining of cultured rat neurons and glia showing strong staining of neuronal cilia using our anti-adenylate cyclase III antibody (cat. 85-AC3, 1:500, red) and axonal and dendritic staining of alpha II spectrin (cat. 98-A2SM,1:500, green) revealing the submembranous cytoskeleton and DNA (blue).
    detail
  •  - Anti-Adenylate Cyclase III Antibody AN1298
    Western blot of rat cortical lysate showing specific immunolabeling of the ~160 kDa adenylate cyclase III protein.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P21932
Reactivity Bovine
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 128936 Da
Additional Information
Gene ID 64508
Other Names AC-III antibody, AC3 antibody, ADCY3 antibody, ADCY3_HUMAN antibody, adenylate cyclase 3 antibody, Adenylate cyclase antibody, Adenylate cyclase type 3 antibody, Adenylate cyclase type III antibody, Adenylyl cyclase 3 antibody, ATP pyrophosphate lyase antibody, ATP pyrophosphate-lyase 3 antibody, olfactive type antibody
Target/Specificity Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).
Dilution WB~~1:1000
IHC~~1:100~500
Format Antigen Affinity Purified
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAnti-Adenylate Cyclase III Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
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citation

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Background

Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).

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$ 430.00
Cat# AN1298
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