ADAP1
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | O75689 |
Reactivity | Human, Rat |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 3E2D9 |
Isotype | Mouse IgG1 |
Calculated MW | 43.4kDa |
Immunogen | Purified recombinant fragment of human ADAP1 (AA: 240-370) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 11033 |
---|---|
Other Names | GCS1L; CENTA1; P42ip4 |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADAP1 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADAP1 |
---|---|
Synonyms | CENTA1 |
Function | GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). |
Cellular Location | Nucleus. Cytoplasm. Note=Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase |
Tissue Location | Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes. |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Biol Chem. 2014 Nov 1;395(11):1321-40.2.Neurochem Int. 2011 Nov;59(6):936-44.
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