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SPATA5L1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BVQ7 |
| Other Accession | NP_076968.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 80710 Da |
| Antigen Region | 585-613 aa |
| Gene ID | 79029 |
|---|---|
| Other Names | Spermatogenesis-associated protein 5-like protein 1, SPATA5L1 |
| Target/Specificity | This SPATA5L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-613 amino acids from the C-terminal region of human SPATA5L1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SPATA5L1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AFG2B (HGNC:28762) |
|---|---|
| Function | ATP-dependent chaperone part of the 55LCC heterohexameric ATPase complex which is chromatin-associated and promotes replisome proteostasis to maintain replication fork progression and genome stability. Required for replication fork progression, sister chromatid cohesion, and chromosome stability. The ATPase activity is specifically enhanced by replication fork DNA and is coupled to cysteine protease- dependent cleavage of replisome substrates in response to replication fork damage. Uses ATPase activity to process replisome substrates in S- phase, facilitating their proteolytic turnover from chromatin to ensure DNA replication and mitotic fidelity (PubMed:38554706). Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle. Nucleus {ECO:0000250|UniProtKB:D4A2B7} |
| Tissue Location | Expressed in both neurons and glia during embryonic and adult stages of brain development. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 150.00
$ 385.00
Cat# AP11262b
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