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K1324 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q6UXG2 |
| Other Accession | NP_065826.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 111382 Da |
| Antigen Region | 704-732 aa |
| Gene ID | 57535 |
|---|---|
| Other Names | UPF0577 protein KIAA1324, Estrogen-induced gene 121 protein, KIAA1324, EIG121 |
| Target/Specificity | This K1324 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-732 amino acids from the C-terminal region of human K1324. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | K1324 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ELAPOR1 (HGNC:29618) |
|---|---|
| Function | May protect cells from cell death by inducing cytosolic vacuolization and up-regulating the autophagy pathway (PubMed:21072319). May play a role in apoptosis and cell proliferation through its interaction with HSPA5 (PubMed:26045166). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in normal endometrium but overexpressed in endometroid tumors. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
K1324 may play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Araki, T., et al. Gene Expr. Patterns 7(6):666-671(2007)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Deng, L., et al. Clin. Cancer Res. 11(23):8258-8264(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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