GPR97 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q86Y34 |
Other Accession | NP_740746.4 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 60861 Da |
Antigen Region | 103-130 aa |
Gene ID | 222487 |
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Other Names | Probable G-protein coupled receptor 97, G-protein coupled receptor PGR26, GPR97, PGR26 |
Target/Specificity | This GPR97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-130 amino acids from the N-terminal region of human GPR97. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GPR97 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADGRG3 (HGNC:13728) |
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Synonyms | GPR97, PGR26 |
Function | Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298). Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins (PubMed:22575658). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed in cultured primary dermal lymphatic endothelial cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GPR97 is an orphan receptor.
References
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Bjarnadottir, T.K., et al. Genomics 84(1):23-33(2004)
Vassilatis, D.K., et al. Proc. Natl. Acad. Sci. U.S.A. 100(8):4903-4908(2003)
Fredriksson, R., et al. FEBS Lett. 531(3):407-414(2002)
Kuznicki, J., et al. Cell Biol. Int. Rep. 3(1):17-23(1979)
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