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ADFP Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 4
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q99541 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48075 Da |
| Antigen Region | 186-214 aa |
| Gene ID | 123 |
|---|---|
| Other Names | Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP, PLIN2, ADFP |
| Target/Specificity | This ADFP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the Central region of human ADFP. |
| Dilution | WB~~1:2000 IHC-P~~1:600 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ADFP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLIN2 (HGNC:248) |
|---|---|
| Synonyms | ADFP |
| Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P43883}; Peripheral membrane protein {ECO:0000250|UniProtKB:P43883}. Lipid droplet |
| Tissue Location | Milk lipid globules.. |
Provided below are standard protocols that you may find useful for product applications.
Background
Adipocyte differentiation-related protein is associated with the globule surface membrane material. This protein is a major constituent of the globule surface. Increase in mRNA levels is one of the earliest indications of adipocyte differentiation.
References
Kimmel, A.R., et al. J. Lipid Res. 51(3):468-471(2010)
Kotokorpi, P., et al. Mol. Pharmacol. 77(1):79-86(2010)
Minnaard, R., et al. J. Clin. Endocrinol. Metab. 94(10):4077-4085(2009)
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