Anti-NRBP1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9UHY1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59845 Da |
Gene ID | 29959 |
---|---|
Other Names | BCON3; NRBP; Nuclear receptor-binding protein |
Target/Specificity | Recognizes endogenous levels of NRBP1 protein. |
Dilution | WB~~1/500 - 1/1000 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | NRBP1 |
---|---|
Synonyms | BCON3 {ECO:0000312|EMBL:AAF21967.1}, NRB |
Function | Required for embryonic development (By similarity). Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes (By similarity). May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases (PubMed:11956649). Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication (PubMed:15084397). |
Cellular Location | Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia |
Tissue Location | Ubiquitously expressed in all tissues examined with high levels in the testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to NRBP1
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