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Anti-KCNMB2 Antibody

Rabbit polyclonal antibody to KCNMB2

     
  • WB - Anti-KCNMB2 Antibody AP59792
    Western blot analysis of KCNMB2 expression in U87MG (A), SP20 (B), H9C2 (C) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession Q9Y691
Other Accession Q9CZM9
Reactivity Human, Mouse, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 27130 Da
Additional Information
Gene ID 10242
Other Names Calcium-activated potassium channel subunit beta-2; BK channel subunit beta-2; BKbeta2; Hbeta2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; Hbeta3; K(VCA)beta-2; Maxi K channel subunit beta-2; Slo-beta-2
Target/Specificity Recognizes endogenous levels of KCNMB2 protein.
Dilution WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name KCNMB2
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human KCNMB2. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP59792
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