Anti-AHA1 Antibody
Rabbit polyclonal antibody to AHA1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
---|---|
Primary Accession | O95433 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38274 Da |
Gene ID | 10598 |
---|---|
Other Names | C14orf3; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38 |
Target/Specificity | Recognizes endogenous levels of AHA1 protein. |
Dilution | WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | AHSA1 |
---|---|
Synonyms | C14orf3 |
Function | Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co- chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). |
Cellular Location | Cytoplasm, cytosol. Endoplasmic reticulum. Note=May transiently interact with the endoplasmic reticulum |
Tissue Location | Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human AHA1. The exact sequence is proprietary.
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