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Anti-SHANK2 Antibody
Rabbit polyclonal antibody to SHANK2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP |
|---|---|
| Primary Accession | Q9UPX8 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 201261 Da |
| Gene ID | 22941 |
|---|---|
| Other Names | CORTBP1; KIAA1022; PROSAP1; SH3 and multiple ankyrin repeat domains protein 2; Shank2; Cortactin-binding protein 1; CortBP1; Proline-rich synapse-associated protein 1 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SHANK2. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100) IP~~N/A |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SHANK2 |
|---|---|
| Synonyms | CORTBP1, KIAA1022, PROSAP1 |
| Function | Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. |
| Cellular Location | Apical cell membrane. Cytoplasm. Synapse. Postsynaptic density. Cell projection, growth cone. Cell projection, dendritic spine. Note=Colocalizes with cortactin in growth cones in differentiating hippocampal neurons Colocalized with PDE4D to the apical membrane of colonic crypt cells (By similarity). |
| Tissue Location | Isoform 3 is present in epithelial colonic cells (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SHANK2. The exact sequence is proprietary.
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