Anti-NUB1 Antibody
Rabbit polyclonal antibody to NUB1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | Q9Y5A7 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 70538 Da |
Gene ID | 51667 |
---|---|
Other Names | NYREN18; NEDD8 ultimate buster 1; Negative regulator of ubiquitin-like proteins 1; Renal carcinoma antigen NY-REN-18 |
Target/Specificity | Recognizes endogenous levels of NUB1 protein. |
Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | NUB1 |
---|---|
Synonyms | NYREN18 |
Function | Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. |
Cellular Location | Nucleus. Note=Predominantly nuclear |
Tissue Location | Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2 |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NUB1. The exact sequence is proprietary.
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