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Anti-EB2 Antibody
Rabbit polyclonal antibody to EB2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q15555 |
| Other Accession | Q8R001 |
| Reactivity | Human, Mouse, Rat, Monkey, Chicken, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37031 Da |
| Gene ID | 10982 |
|---|---|
| Other Names | RP1; Microtubule-associated protein RP/EB family member 2; APC-binding protein EB2; End-binding protein 2; EB2 |
| Target/Specificity | Recognizes endogenous levels of EB2 protein. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MAPRE2 |
|---|---|
| Synonyms | RP1 |
| Function | Adapter protein that is involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. Therefore, ensures mitotic progression and genome stability (PubMed:27030108). Acts as a central regulator of microtubule reorganization in apico-basal epithelial differentiation (By similarity). Plays a role during oocyte meiosis by regulating microtubule dynamics (By similarity). Participates in neurite growth by interacting with plexin B3/PLXNB3 and microtubule reorganization during apico-basal epithelial differentiation (PubMed:22373814). Also plays an essential role for cell migration and focal adhesion dynamics. Mechanistically, recruits HAX1 to microtubules in order to regulate focal adhesion dynamics (PubMed:26527684). |
| Cellular Location | Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules |
| Tissue Location | Expressed in different tumor cell lines. Up- regulated in activated B- and T-lymphocytes |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EB2. The exact sequence is proprietary.
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