Anti-Ataxin 1 (pS775) Antibody
Rabbit polyclonal antibody to Ataxin 1 (pS775)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF/IC, IHC |
---|---|
Primary Accession | P54253 |
Other Accession | P54254 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 86923 Da |
Gene ID | 6310 |
---|---|
Other Names | ATX1; SCA1; Ataxin-1; Spinocerebellar ataxia type 1 protein |
Target/Specificity | Recognizes endogenous levels of Ataxin 1 (pS775) protein. |
Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ATXN1 |
---|---|
Synonyms | ATX1, SCA1 |
Function | Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development (By similarity). |
Cellular Location | Cytoplasm. Nucleus Note=Colocalizes with USP7 in the nucleus |
Tissue Location | Widely expressed throughout the body. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Ataxin 1 (pS775). The exact sequence is proprietary.
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