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InsP 3-kinase C Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q96DU7 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 75207 Da |
| Gene ID | 80271 |
|---|---|
| Other Names | ITPKC; IP3KC; Inositol-trisphosphate 3-kinase C; Inositol 1; 4, 5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase C |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | ITPKC (HGNC:14897) |
|---|---|
| Synonyms | IP3KC |
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5- trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis (PubMed:11085927, PubMed:12747803). Can phosphorylate inositol 2,4,5- triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity). |
| Cellular Location | Nucleus. Cytoplasm. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity {ECO:0000250|UniProtKB:Q80ZG2} |
| Tissue Location | Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
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