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Anti-ITPKC Antibody
Rabbit polyclonal antibody to ITPKC
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q96DU7 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 75207 Da |
| Gene ID | 80271 |
|---|---|
| Other Names | IP3KC; Inositol-trisphosphate 3-kinase C; Inositol 1, 4, 5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase C |
| Target/Specificity | Recognizes endogenous levels of ITPKC protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ITPKC (HGNC:14897) |
|---|---|
| Synonyms | IP3KC |
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5- trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis (PubMed:11085927, PubMed:12747803). Can phosphorylate inositol 2,4,5- triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity). |
| Cellular Location | Nucleus. Cytoplasm. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity {ECO:0000250|UniProtKB:Q80ZG2} |
| Tissue Location | Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ITPKC. The exact sequence is proprietary.
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